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Immune
Purity
99.6%
HPLC Tested
Ms verified
Coa included
KPV
$99.95
Half-life
1–2 hours
Purity
≥ 99.6%
Mw
342.4 g/mol
In stock
KPV constitutes a naturally derived tripeptide consisting of lysine, proline, and valine, stemming from alpha-melanocyte-stimulating hormone (α-MSH). It stands out due to its robust anti-inflammatory and antibacterial capabilities. The peptide operates by penetrating cellular structures and binding to key inflammatory mediators. By suppressing signaling cascades like NF-κB and mitogen-activated protein (MAP) kinase, it diminishes the synthesis of proinflammatory mediators, including interleukins 1 and 6. Ultimately, this mechanism aids in balancing immune activity and mitigating inflammatory processes.
Mechanism of action
Derived from α-MSH C-terminus; enters cells via PepT1 transporter, accumulates in nucleus, inhibits NF-κB translocation to suppress pro-inflammatory cytokine gene expression in epithelial and immune cell models without broad immunosuppression.
Compound Profile
- Category Anti-Aging, Immunity and Defense
- Molecular weight 342.4 g/mol
- Half-life 1–2 hours
- Minimum purity ≥ 99.6%
- Form Lyophilized powder
- Solvent Bacteriostatic water (BAC)
Storage
Critical Storage
Lyophilized: 2–8°C preferred. Post-reconstitution: 4°C, 5–7 days.
Reconstitution
Add 1–2 mL sterile or bacteriostatic water. Use immediately or refrigerate. Do not freeze post-reconstitution.
Quality Assurance & COA
HPLC Analysis
Identity + purity
Mass Spectrometry
Identity + purity
Sterility Testing
USP <71> compliant
Certificate of Analysis
Full COA ships with every order including HPLC trace, mass spec, and per-batch purity percentage.
Certifications
- Dual Third-Party Lab Tested
- HPLC Purity Verified
- Mass Spec Identity Confirmed
- Cold-Chain Certified Shipping
